منابع مشابه
HIV therapy: managing resistance.
O the last years, a number of potent drugs have been developed that inhibit HIV-1 replication in vivo. Treatment regimes involving a combination of three or more different drugs can induce a decline in virus load by several orders of magnitude, as well as a significant rise in the CD4 cell count. The drugs currently in use mainly fall into two classes: reverse transcriptase inhibitors prevent i...
متن کاملManaging around Waterhemp Resistance
Few weed species have gained so much attention over the past decade as waterhemp. Waterhemp has gone from an obscure weed species in the 1980s to a species that has achieved widespread distinction throughout most of the Midwest. This species gained its notoriety in the early 1990s when it began appearing in many corn and soybean fields in Illinois, Iowa, Kansas, and Missouri. In these fields AL...
متن کاملChromium Therapy for Insulin Resistance Associated with HIV-Disease.
OBJECTIVE With the advent of highly active anti-retroviral therapy, HIV disease has become a chronic condition, but with a number of metabolic complications including insulin resistance and diabetes mellitus, dyslipidemia and hypertension and an increased incidence of atherosclerosis. The aim of the current study was to test the safety and efficacy of chromium picolinate for HIV- associated ins...
متن کاملOptimal Antiviral Switching to Minimize Resistance Risk in HIV Therapy
The development of resistant strains of HIV is the most significant barrier to effective long-term treatment of HIV infection. The most common causes of resistance development are patient noncompliance and pre-existence of resistant strains. In this paper, methods of antiviral regimen switching are developed that minimize the risk of pre-existing resistant virus emerging during therapy switches...
متن کاملInternational perspectives on adherence and resistance to HIV antiretroviral therapy
Public health debates about providing HIV antiretroviral therapy to impoverished HIV+ populations are based on the relationship between adherence and risk of drug resistance to HIV antiretroviral therapy. Early justifications for withholding antiretroviral therapy from marginalized domestic populations, such as drug users and the homeless, were mistaken for two reasons. First, levels of adheren...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2000
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.97.15.8193